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For example, metformin, a widely used antidiabetic drug, inhibits mitochondrial complex I, leading to AMPK activation and downstream inhibition of mTORC1

British Journal of Pharmacology / NIHMS PMC (2008) 6

The KolmogorovSmirnov test was used to assess the normality of data distribution

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393 However, clinical and preclinical indications disclose that zinc is persistently and significantly reduced in the early stage of PC compared with the normal or benign pancreas tissues, which is an essential malignant event